CBG (Cannabigerol) – Introduction
Cannabigerol (CBG), is a phytocannabinoid, which is converted in other types, thanks to several enzymes activity, improving that it can be really important to cannabis therapeutic use.
It is a non-toxic cannabinoid detected in cannabis plants and other plants, such as Helichrysum umbraculigerum. Cannabigerol is the beginning of the production of many other cannabinoids, like cannabidiol (CBD), tetrahydrocannabinol (THC), etc. In the early stages of growing, cannabis has a significant quantity of CBG before being converted into other precious compounds. Cannabigerol is another substance found in cannabis that has gained relatively the trust of so many people in their daily diet and activities thanks to its beneficial properties. Below we will refer to more details about CBG, studies, and side effects.
What is Cannabigerol (CBG)?
Cannabigerol (CBG) is one of the cannabinoids found in cannabis under the non-acidic form of cannabigerolic acid (CBGA). It is known as the precursor of several cannabinoids (mother of all the cannabinoids), like cannabidiol (CBD), tetrahydrocannabinol (THC), and cannabichromene (CBC). In most cannabis strains, cannabigerol does not exceed 1-2%, while it is observed in great amounts when the plant is in the initial phase of growth. Therefore, there are strains that have low THC and high CBG coming from a cross of phenotypes that are rich in cannabigerol, such as White CBG, Jack Frost CBG, White Whale, and many more. Cannabigerol was almost considered an outsider in comparison to cannabidiol and tetrahydrocannabinol, even if it was detected by Yehiel Gaoni and Raphael Mechoulam, in 1964. Therefore, lately is gaining more “space” in the scientific community and the people’s daily life, thanks to the beneficial properties in the organism, and mostly thanks to the strong anti-inflammatory effect.
Cannabigerol was almost considered an outsider in comparison to cannabidiol and tetrahydrocannabinol, even if it was detected by Yehiel Gaoni and Raphael Mechoulam, in 1964. Therefore, lately is gaining more “space” in the scientific community and the people’s daily life, thanks to the beneficial properties in the organism, and mostly thanks to the strong anti-inflammatory effect.
The endocannabinoid system is an endogenous system detected in humans and animals, which contributes to the balance of main organism functions. It produces endocannabinoids, like anandamide, and 2-Arachidonoylglycerol (2-AG), found all over our body from the brain to the cells of our immune system. A distinctive feature of endocannabinoids is autophagy (self-eating), which is an intracellular process when cell regeneration occurs by removing the damaged components. The scientists observed three endocannabinoid receptors, CB1, CB2, and CB3, which are detected in various parts of our body, activating a number of physiological processes.
The endocannabinoid system is responsible for the balance of the internal organism conditions, leading to the prevention of several diseases. This endogenous system affects the appetite, metabolism, sense of pain, sleep, mood, temperature, memory, nervous system, reproduction, cardiovascular, and immune system.
Cannabigerol function (CBG)
Cannabigerol along with the other cannabinoids «communicate» with the endocannabinoids of the organism. In the CBG case, it seems to imitate the endocannabinoid system, because it is binding with neuron receptors CB1 and CB2 enhancing anandamide function, which contributes to a balanced mood, appetite, pain feeling, and sleep. It has non-psychoactive effects, hence like cannabidiol, can balance the side-effects of the THC psychoactive effects, strengthening at the same time the effects of the cannabinoids on the organism.
Effects, Beneficial properties of CBG Cannabigerol
Cannabigerol has drawn the interest of scientists the last few years, as it seems to have beneficial properties for the organism with no psychoactive effect, such as the balanced role that has to the side-effects of THC. Naturally, we need more research for better results, even if the data until now are pretty encouraging.
Inflammations and digestive system
In a 2013 study, the scientists concluded that cannabigerol should be studied further, especially in cases when it is observed as Inflammatory bowel disease (IBD) because it seems to significantly reduce the inflammation and the production of nitric oxide. Also, CBG appears to have strong anti-inflammatory effects, especially in cases of Idiopathic Inflammatory Bowel Disorders, that encompass Crohn’s disease and ulcerative colitis.
According to a study, published in 2015, cannabigerol has neuroprotective effects, fortifying the neuron brain cells from deterioration, especially in neurodegenerative diseases, such as Huntington’s disease and multiple sclerosis, which could give significantly effective results.
It is worth referring to the antibacterial effect of CBG when it comes to cases like the bacterial infection from Staphylococcus aureus or Mycobacterium avium intracellulare.
Chronic pain, anxiety
According to a study, published in the journal Therapeutics And Clinical Risk Management, cannabigerol appears to have a strong analgesic effect even more than tetrahydrocannabinol (THC). So, it could be effective in cases of chronic pain thanks to the muscle relief effect that appears to have.
Cannabigerol keeps skin cells hydrated, while it has anti-fungal, antibacterial effects, soothing and protecting the skin from various infections. It is worth underlining that during the 1950s there were cannabis products for various skin conditions for topic use, with impressive results.
Cannabigerol is a potent vasodilator with important neuroprotective properties, as mentioned above, and has been shown to relieve intraocular pressure and is important in the treatment of glaucoma.
CBG is known for its anti-septic effects, as studies refer that is effective against the superbug MRSA.
Cannabigerol is a cannabinoid that gives hope for the treatment of various cancers, such as breast, liver, lung, pancreas, skin, ovarian, kidneys, and colon cancers. This is because cannabigerol blocks the receptors that cause cancer cells to grow.
CBG has significant therapeutic effects in diseases of the Central Nervous System (CNS) thanks to its neuroprotective effect, preventing further damages to the system.
What are the beneficial properties of cannabigerol? (Brief summary)
- Neuro-protective effect
- Strong anti-inflammatory effect
- Strong anti-emetic effect
- Anti-cancer effect
- Promotes and enhances bones protection
- Against insomnia
- Stimulates appetite
- Stimulates brain cells
Disorders treated by cannabigerol
Cannabigerol may have therapeutic potential in treating several diseases and disorders:
- Nervous system diseases
- Neurodegenerative disorders
- Inflammatory Bowel Disease
- Ulcerative colitic
- Huntington’s disease
- Crohn’s disease
- Staphylococcus aureus (MRSA)
- Chronic pain
- Inflammatory disorders
- Cancer symptoms
- Dysfunction of urinary system
- Lower appetite because of chemo-therapies
CBG oil dosage: How much should I take?
Like CBD, the quantity/dosage of CBG varies from person to person. It depends on our personal needs if used in combination with cannabidiol for therapeutic or another reason.
The first step is to evaluate the percentage of CBG in the oil: enecta G500 contains 1.5 mg of cannabigerol in each drop. The second step is to take into consideration the variations in the metabolic response from person to person, according to the bibliography, and the testimonials that show positive same results even at different dosages, under normal conditions (age, height, weight).
The correct answer is to “hear” our body, starting with a few drops to reach the optimal amount of the so-called “Therapeutic window” based on our individual needs and always after consulting our physician.
Until now, cannabigerol seems to have beneficial properties to the organism, while it has a non-psychoactive effect and it is safe for use without side effects. Of course, when we use products, such as CBG oil, we should consult our doctor especially if we are receiving any kind of medication. In any case, it can not replace a balanced diet or a medical prescription.
We can enjoy the beneficial properties of cannabigerol in various ways, to choose the one that we prefer. There are CBG oils, CBG cannabis flowers, CBD&CBG crystals, while there are also edibles with cannabigerol.
The CBG contained in the products comes from legal cannabis crops in Greece and Europe, without pesticides and herbicides, following the European standards.
CBG (Cannabigerol) in which point is the research?
A study published by the Pharmacy of the University of Naples Federico II, in collaborations with the doctors of the Diagnostic Department of the Pellegrini Hospital of Naples and the researchers from CNR in Pozzuoli, show CBG effects in the case of a persistent inflammation concluding that cannabigerol is a new therapeutic opportunity for those suffering from this disorder.
A study published in 2009 by the Journal of Pharmacology and Therapeutics, refers that Cannabigerol (CBG) can contribute to the increased of eye fluid drainage and therefore has the potential to help reduce eye pressure: an additional opportunity to treat glaucoma.
In the case of inflammatory bowel disease, CBG offers all its anti-inflammatory and analgesic properties, such as Crohn’s disease, which we have mentioned in the past, emphasizing the positive contribution of CBD (Click here).
For example, we list three top products with cannabigerol, which you could include in your daily life.
Enecta has decided to invest in Cannabigerol research, presenting in 2018, two interesting products in the European market, G 500 CBG Oil, Cannabigerol Oil, Premium Oil with CBG, and pure CC 500 CBG Crystals.
It is a product of premium quality, high nutritional value, rich in CBG, flavonoids, vitamin E, and natural tocopherols. Ideal to boost the immune system and the general body wellness.
A natural product without pesticides or herbicides extracted directly from our plants in Italy and tested by independent laboratories to ensure its safety and quality.
CBG is also described as the father of all cannabinoids and this is no coincidence: as a father CBG “bends” to nature’s needs, giving life to other cannabis compounds such as CBD and THC.
CBG cannabis flower Briosa; Another innovation by the famous brand Terre Di Cannabis. A refined flower of premium quality, with unique flavors, rich in resin and cannabigerol, ready for use in a vaporizer, or in a beverage. Furthermore, this cannabis strain has terpenes, such as linalool and ocimene, which in combination with the flavonoids could contribute to the reduction of oxidative stress, offering the psychophysical balance.
CBG cannabis flower Fatale: This cannabis strain is here to surprise everybody. It has a high percentage in cannabigerol (20%), while it is ideal for chronic pain, migraines, menstrual syndrome, and rheumatism, thanks to b-caryophyllene and terpinolene, which have a strong antibacterial, anti-inflammatory, and analgesic effect.
Another cannabinoid with significant beneficial properties against a number of diseases and ailments of the body. Without side effects hence with multiple benefits to our overall health and wellness and proper functioning of our body.
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